Interested in learning more? Schedule a Lunch & Learn for your team

ProBiora Pro Group

Probiotics for Your Teeth and Gums

ProBioraPro is the professional-strength probiotic mint that helps restore and maintain the proper balance of beneficial oral bacteria after professional cleanings, treatments and procedures.

What are ProBioraPro Oral-care Probiotics?

You’re probably familiar with digestive probiotics such as yogurt, sauerkraut, kimchi, and kombucha. ProBiora Health® creates probiotics designed specifically for oral health.

Containing our most highly concentrated blend of patented probiotics, called ProBiora3®, ProBioraPro helps extend the benefits of your professional treatment.

When dissolved in the mouth, the beneficial bacteria flood the mouth and crowd out the harmful bacteria. The all-natural ProBioraPro:
• Adheres to teeth and below the gum line
• Promotes positive gum and teeth health and crowds out undesirable bacteria that can cause bad breath
• Releases continuous low doses of hydrogen peroxide that naturally whiten teeth

More About the Science

Take one mint once-a-day


Support dental health
Naturally supports your gum and tooth health.


100% Natural
Restore your natural balance of beneficial bacteria.


Calories Per Serving: 1 Total Fat: 0g Sodium: 0mg Total Carbohydrate: 0g Protein: 0g Active Ingredient: 125 Million CFU ProBiora3® (Streptococcus uberis KJ2®, Streptococcus oralis KJ3®, Streptococcus rattus JH145®) Inactive Ingredients: Isomalt, Inulin, Glyceryl Behenate, Peppermint Flavor (natural), Spearmint Flavor (natural), Stevia Rebaudioside A (97%) Contains: Milk. Trace levels of milk proteins from probioticsfermentation. Soy, wheat, nut and gluten free.

Our Guarantee

For Product shipments direct to consumer, PBH offers a 30 day money back guarantee, less shipping and handling. This applies once per household per Product. Refund will be processed within 10 business days after returned Product is received by PBH. Otherwise, no Product will be accepted for return unless packaging is damaged in shipment. Buyer must notify PBH in writing, including photo documentation, and any damaged Product must be returned within 30 days of shipment for exchange of like Product. All shipping to be paid by Buyer. Refunds will not be issued for non-delivered items if shipping address is incorrect on order.

The Science of Probiotics — Restoring the Balance of a Healthy Mouth.

You may be familiar with probiotics for digestive and immune health. Probiotics use beneficial bacteria to replace harmful ones and promote health. ProBioraPro® is the first probiotic powder specifically designed for your patient’s oral and dental care. Villains and Superheroes in the MouthIn the 1980s, a researcher named Jeffrey Hillman, PhD, DDS, wondered, “Is there a biological mechanism that helps counteract bad bacteria and, instead, promoted a healthy mouth?” Conducting landmark research at the Harvard-affiliated Forsyth Institute in Boston and later at the University of Florida Dental School, Hillman discovered that there are “good” bacteria that can crowd out the “bad” bacteria and restore the natural balance of a healthy mouth. From this discovery, Dr.Hillman created ProBiora3, a patented blend of beneficial “superhero” bacteria that crowd out the “villains” and support overall gum and tooth health. Now with 30 years of clinical research to back it up, ProBiora3 is the active ingredient in ProBioraPro and other ProBiora Health oral care probiotic products. Harnessing Probiotics for Your Oral HealthThe way ProBioraPro oral care probiotics works is simple: Freeze-dried live microorganisms—“good,” or beneficial bacteria—are introduced to the mouth in the probiotic mint. As the mint dissolves in the mouth, the saliva hydrates the probiotic bacteria. They seek out their natural habitat, immediately migrating to the mouth tissue, gums, gum pockets and tooth surfaces where they will “live” and compete with the pathogens. These beneficial bacteria restore the balanced oral biome that’s so critical to good oral health. Using ProBiora Health probiotics just once a day is all it takes to support healthier gums and teeth and fresher breath.

ProBioraPro is easy to use

We made good oral health super simple. Just dissolve one ProBioraPro mint in your mouth once a day. In 30 days or less, you’ll notice improved gum health, fresher breath and whiter teeth.

sun-moon You can take ProBioraXtra at any time of day and achieve results, but taking ProBioraXtra at bedtime is more effective!


After brushing your teeth, let ProBioraXtra mint dissolve on your tongue.


Notice healthier teeth and gums, whiter teeth and fresher breath in as little as thirty days.

For Best Results

Keep your ProBioraXtra mints in their packaging until needed. Store in a cool, dry place when not on the go. Avoid exposure to heat and humidity.


Effective to use with dental appliances and sleep aids.

If you use mouthwash, wait 30 minutes before using ProBioraXtra.

Frequently Asked Questions

What are probiotics?

Probiotics are live microbial organisms that are naturally present throughout the body. They are often referred to as “beneficial” or “good” bacteria. There are specific strains of probiotics that are beneficial for helping to make your pets’ breath fresher and promoting cleaner, whiter teeth. These probiotics are different from the good bacteria used to promote digestive health. The good bacteria in ProBioraPro work by crowding out the bad bacteria that cause bad breath, resulting in fresher breath and cleaner, whiter teeth.

What’s the difference between ProBioraPro and ProBioraPlus or ProBioraXtra?

ProBioraPro is a professional strength version of our ProBioraPlus product. It is also bottled as a 90 day supply instead of a 30 day supply.

What are the ingredients in ProBioraPro?

ACTIVE INGREDIENT: 125 Million CFU ProBiora3® (Streptococcus uberis KJ2®, Streptococcus oralis KJ3®, Streptococcus rattus JH145®) INACTIVE INGREDIENTS: Isomalt, Inulin, Glyceryl Behenate, PeppermintFlavor (natural), Spearmint Flavor (natural), Stevia Rebaudioside A (97%) Contains: Milk. Trace levels of milk proteins from probioticsfermentation. Soy, wheat, nut and gluten free.

How long should patients use ProBioraPro?

ProBioraPro is typically used following a professional cleaning to reestablish the balance of healthy, essential probiotics in the mouth. Patients should continue to use ProBioraPro for ongoing maintenance because the beneficial probiotic strains need regular replenishment to help maintain the proper bacterial balance.

Is ProBioraPro safe for dentures, caps, crowns, braces, dental appliances and sleep aids?

Absolutely. Unlike other commercially available whitening products, the ProBioraPro oral care probiotic mint is completely safe and effective for use with dentures, veneers, caps, dental bridges, crowns, braces, dental appliances and sleep aids. It’s also a great way to provide additional support in maintaining gum and tooth health for those who wear oral braces.

How long until I see results?

ProBioraPro starts to work immediately. Most patients notice a difference within 30 days of use.

Does ProBioraPro interfere with any medications?

ProBioraPro mints are 100% natural with a mild mint flavor and there are no known interactions with supplements, medications or mouthwash. Patients should consult their physician with questions regarding their medication. For optimal results, patients should wait at least 30 minutes after rinsing with mouthwash to use ProBioraPro. As with use for any medication, it is suggested that you check with your Doctor/Dentist or Pharmacist for more information.

Does ProBioraPro need to be refrigerated?

No. ProBioraPro is shelf-stable at room temperature. The beneficial bacteria in this revolutionary probiotic mint are freeze dried and activate on contact with your saliva.

Can a patient eat or drink anything after the mint dissolves?

A patient should not eat or drink anything for 30 minutes after the ProBioraPro mint has dissolved in the mouth. This gives the probiotic bacteria time to adhere to tooth and gum surfaces and begin colonization.

“When one looks truly beyond just the packaging, and looks actually at those organisms, and if you have any background in microbiology, you truly appreciate the competitive nature of those selected three organisms and what each one of them individually can do to create an environment by which the pathogens are replaced. And once you replace the pathogens, you’ve lost the etiology and then you’re going to get health.”

—Samuel B. Low, DDS, MS, M.Ed

“One of the reasons why this particular product is so superior to everything else on the marketplace today and to my knowledge is the fact that we have 30 years of research that back up the efficacy of those particular bacterial strains in the oral cavity. So there’s a lot of science to back up the claims that those products actually work.”

—Martin Handfield, M.Sc., Ph.D.

“There are lots of probiotics on the market, and there are quite a few oral probiotics. What is unique to ProBioraPro is that we do have the three species of bacteria that are native to the mouth.”

—Lora Hooper, BSDH, RDH, EFDA

“Like sending in the good troops to drive out the bad.”
—Witt Wilkerson, DDS

No two mouths are the same, but they all have something in common: bacteria.

You see, inside your mouth are billions of bacteria, bad and good. The bad cause gum disease and tooth decay. But the good keep your teeth and gums healthy. ProBioraPro’s unique blend of probiotics repopulates your mouth with “good” bacteria that crowd out the bad, giving you healthier teeth and gums and fresher breath.

As Dr. Witt Wilkerson says, it’s “like sending in the good troops to drive out the bad.” Watch Dr. Wilkerson and other leading dentists talk about why ProBiora Health oral care probiotics are right for you.

Learn More

Discover the advantages of being a ProBioraPro Practice.
Pro for Your Patients is a Plus for Your Dental Practice.